Stephen M Davis Selected Research

Tissue Plasminogen Activator (Alteplase)

1/2022	Comparison of tenecteplase with alteplase for the early treatment of ischaemic stroke in the Melbourne Mobile Stroke Unit (TASTE-A): a phase 2, randomised, open-label trial.
1/2022	Safety and Efficacy of Tenecteplase in Older Patients With Large Vessel Occlusion: A Pooled Analysis of the EXTEND-IA TNK Trials.
1/2022	Reduced Severity of Tissue Injury Within the Infarct May Partially Mediate the Benefit of Reperfusion in Ischemic Stroke.
1/2022	Thrombectomy versus Medical Management in Mild Strokes due to Large Vessel Occlusion: Exploratory Analysis from the EXTEND-IA Trials and a Pooled International Cohort.
1/2022	Tenecteplase versus Alteplase for Stroke Thrombolysis Evaluation Trial in the Ambulance (Mobile Stroke Unit-TASTE-A): protocol for a prospective randomised, open-label, blinded endpoint, phase II superiority trial of tenecteplase versus alteplase for ischaemic stroke patients presenting within 4.5 hours of symptom onset to the mobile stroke unit.
11/2021	Association between pre-treatment perfusion profile and cerebral edema after reperfusion therapies in ischemic stroke.
1/2021	Association of Reperfusion After Thrombolysis With Clinical Outcome Across the 4.5- to 9-Hours and Wake-up Stroke Time Window: A Meta-Analysis of the EXTEND and EPITHET Randomized Clinical Trials.
1/2021	Tenecteplase vs Alteplase Before Endovascular Therapy in Basilar Artery Occlusion.
11/2020	Intravenous alteplase for stroke with unknown time of onset guided by advanced imaging: systematic review and meta-analysis of individual patient data.
1/2020	Effect of Intravenous Tenecteplase Dose on Cerebral Reperfusion Before Thrombectomy in Patients With Large Vessel Occlusion Ischemic Stroke: The EXTEND-IA TNK Part 2 Randomized Clinical Trial.

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Stephen M Davis Research Topics

Disease

127	Stroke (Strokes) 02/2022 - 04/2002
103	Ischemic Stroke 02/2022 - 01/2003
26	Infarction (Infarctions) 01/2022 - 07/2002
17	Cerebral Hemorrhage 03/2022 - 04/2005
14	Hemorrhage 03/2022 - 10/2006
11	Hematoma 03/2022 - 01/2006
7	Brain Edema (Cerebral Edema) 01/2022 - 08/2013
6	Edema (Dropsy) 01/2022 - 08/2013
6	Intracranial Hemorrhages (Intracranial Hemorrhage) 01/2021 - 02/2006
6	Cerebral Infarction 01/2020 - 01/2006
5	Atrial Fibrillation 10/2019 - 04/2002
4	Arterial Occlusive Diseases (Arterial Occlusive Disease) 01/2022 - 01/2014
4	Hyperglycemia 01/2019 - 07/2002
4	Inflammation (Inflammations) 01/2018 - 06/2008
4	Hypertension (High Blood Pressure) 01/2010 - 04/2002
3	Hemorrhagic Stroke 01/2021 - 03/2009
3	Poisoning 01/2016 - 05/2010
2	Carotid Stenosis (Carotid Artery Stenosis) 10/2019 - 05/2008
2	Thrombosis (Thrombus) 05/2019 - 01/2018
2	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2018 - 03/2016
2	Body Weight (Weight, Body) 01/2018 - 03/2015
2	Lacunar Stroke 07/2016 - 06/2013
2	Ischemia 01/2014 - 08/2004
2	Human Influenza (Influenza) 01/2012 - 03/2010
2	Atherosclerosis 01/2010 - 03/2008
1	Wounds and Injuries (Trauma) 12/2020
1	Multiple Chronic Conditions 01/2020
1	Intracranial Thrombosis (Cerebral Thrombosis) 01/2020
1	Neurologic Manifestations (Neurological Manifestations) 01/2019
1	Hepatitis C 11/2018
1	Coinfection 11/2018
1	Spinal Cord Injuries (Spinal Cord Injury) 01/2018
1	Atrophy 01/2016
1	Opioid-Related Disorders (Opiate Addiction) 12/2015

Drug/Important Bio-Agent (IBA)

62	Tissue Plasminogen Activator (Alteplase)FDA Link 01/2022 - 04/2003
16	Tenecteplase FDA Link 01/2022 - 01/2017
12	Glucose (Dextrose)FDA LinkGeneric 11/2021 - 09/2003
10	Biomarkers (Surrogate Marker)IBA 01/2022 - 04/2004
7	Cytidine Triphosphate (CTP)IBA 01/2020 - 12/2011
6	Blood Glucose (Blood Sugar)IBA 08/2017 - 07/2002
6	Pharmaceutical PreparationsIBA 08/2014 - 10/2005
6	Factor VIIa (Activated Factor VII)IBA 01/2010 - 01/2006
6	recombinant FVIIa (rFVIIa)FDA Link 01/2010 - 01/2006
5	Fibrinolytic Agents (Antithrombotic Agents)IBA 01/2022 - 06/2011
5	CholesterolIBA 10/2019 - 06/2004
5	Neuroprotective AgentsIBA 06/2011 - 12/2006
5	disufenton sodium (NXY 059)IBA 06/2008 - 02/2006
5	Free RadicalsIBA 06/2008 - 02/2006
4	Tranexamic Acid (AMCA)FDA Link 03/2022 - 06/2014
4	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 05/2017 - 05/2008
4	Hemostatics (Antihemorrhagics)IBA 01/2014 - 01/2006
3	Warfarin (Coumadin)FDA LinkGeneric 12/2016 - 05/2008
3	Opioid Analgesics (Opioids)IBA 01/2016 - 05/2010
3	Biological ProductsIBA 01/2016 - 03/2009
3	CreatinineIBA 10/2015 - 03/2007
3	Factor VII (Proconvertin)IBA 01/2010 - 01/2006
3	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 01/2010 - 03/2007
2	Prescription DrugsIBA 12/2015 - 05/2010
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 11/2014 - 01/2005
2	Glyburide (Glibenclamide)FDA LinkGeneric 08/2014 - 01/2014
2	4- Acetamido- 4'- isothiocyanatostilbene- 2,2'- disulfonic Acid (SITS)IBA 03/2014 - 07/2013
2	TESIBA 01/2010 - 03/2008
2	Desmodus rotundus salivary plasminogen activator alpha 1IBA 01/2010 - 03/2009
2	Heparin (Liquaemin)FDA LinkGeneric 04/2003 - 01/2003
1	GadoliniumIBA 01/2022
1	Plasminogen Activators (Plasminogen Activator)IBA 01/2022
1	Dabigatran FDA Link 01/2019
1	idarucizumabIBA 01/2019
1	Indicators and Reagents (Reagents)IBA 12/2018
1	SolutionsIBA 01/2018
1	ORALIT (ORS)IBA 07/2017
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 05/2017
1	Metformin (Glucophage)FDA LinkGeneric 12/2016
1	N-acetylaspartate (N-acetyl aspartate)IBA 01/2016
1	Complement System Proteins (Complement)IBA 01/2016
1	CreatineIBA 01/2016
1	IceIBA 01/2016
1	Inositol (Myoinositol)IBA 01/2016
1	ProteomeIBA 01/2016

Therapy/Procedure

62	Therapeutics 02/2022 - 11/2002
35	Thrombectomy 02/2022 - 03/2015
10	Thrombolytic Therapy 01/2016 - 11/2002
8	Secondary Prevention 10/2019 - 11/2002
7	Stents 01/2019 - 03/2015
5	Time-to-Treatment 05/2019 - 08/2003
4	Treatment Delay 09/2016 - 04/2014
3	Aftercare (After-Treatment) 01/2019 - 07/2013
2	Punctures 01/2022 - 01/2019
2	Embolectomy 01/2021 - 10/2018
2	Contraindications 01/2020 - 01/2018
2	Catheters 01/2020 - 01/2018
2	Craniotomy 01/2018 - 03/2016
1	Subacute Care 12/2020
1	Patient Readmission 12/2020
1	Institutionalization (Institutionalized Persons) 01/2020
1	Carotid Endarterectomy 10/2019
1	Ambulatory Care (Outpatient Care) 11/2018
1	Electrodes (Electrode) 01/2018
1	Prostheses and Implants (Prosthesis) 01/2018
1	Intravenous Infusions 01/2018